{"id":11,"date":"2023-11-10T05:49:08","date_gmt":"2023-11-10T05:49:08","guid":{"rendered":"https:\/\/mioste.ch\/?page_id=11"},"modified":"2023-11-21T15:55:41","modified_gmt":"2023-11-21T15:55:41","slug":"home","status":"publish","type":"page","link":"https:\/\/mioste.ch\/","title":{"rendered":"Home"},"content":{"rendered":"\n<h1>\n\t\tMioste\n\t<\/h1>\n<h4>\n\t\tMedical Innovation and Smart Technologies \n\t<\/h4>\n\t<p>The group \u201cMed\u00adical Inno\u00adva\u00adtion and Smart Tech\u00adnolo\u00adgies (MIOSTE)\u201d was found\u00aded by Ste\u00adfan St\u00fcbinger and Mio\u00addrag Sav\u00adic. The pri\u00adma\u00adry aim is to fos\u00adter advances in clin\u00adi\u00adcal\u00adly ori\u00adent\u00aded research, emerg\u00ading tech\u00adnolo\u00adgies and inno\u00adv\u00ada\u00adtive prod\u00aduct devel\u00adop\u00adment. Prin\u00adci\u00adpal fields of inter\u00adest are trans\u00adla\u00adtion\u00adal med\u00adi\u00adcine includ\u00ading pro\u00adto\u00adtyp\u00ading, exper\u00adi\u00admen\u00adtal sur\u00adgi\u00adcal tech\u00adniques, regen\u00ader\u00ada\u00adtive med\u00adi\u00adcine, applied biotech\u00adnol\u00ado\u00adgy and mol\u00ade\u00adc\u00adu\u00adlar med\u00adi\u00adcine with a focus on body flu\u00adids. Embed\u00added with\u00adin the Uni\u00adver\u00adsi\u00adty Hos\u00adpi\u00adtal Basel, MIOSTE offers an open and inter\u00addis\u00adci\u00adpli\u00adnary research unit for var\u00adi\u00adous dis\u00adci\u00adplines and cre\u00adates strate\u00adgi\u00adcal col\u00adlab\u00ado\u00adra\u00adtions devel\u00adop\u00ading nov\u00adel and prag\u00admat\u00adic approach\u00ades for solv\u00ading com\u00adplex health prob\u00adlems.<\/p>\n<h2>\n\t\tPeople\n\t<\/h2>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/mioste.ch\/wp-content\/uploads\/bb-plugin\/cache\/mioste-miodrag-savic-1-circle.jpg\" alt=\"mioste-miodrag-savic\" title=\"mioste-miodrag-savic\" itemprop=\"image\">\n\t\t\t\t \n\t\t<h4>Miodrag Savic<\/h4>group head\t\t\t\t\t\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/mioste.ch\/wp-content\/uploads\/bb-plugin\/cache\/mioste-stefan-stuebinger-1-circle.jpg\" alt=\"mioste-stefan-stuebinger\" title=\"mioste-stefan-stuebinger\" itemprop=\"image\">\n\t\t\t\t \n\t\t<h4>Stefan St\u00fcbinger<\/h4>co-head\t\t\t\t\t\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/mioste.ch\/wp-content\/uploads\/bb-plugin\/cache\/mioste-tobias-schindler-circle.jpg\" alt=\"mioste-tobias schindler\" title=\"mioste-tobias schindler\" itemprop=\"image\">\n\t\t\t\t \n\t\t<h4>Tobias Schindler<\/h4>project leader\t\t\t\t\t\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/mioste.ch\/wp-content\/uploads\/bb-plugin\/cache\/mioste-martin-sailer-circle.jpg\" alt=\"mioste-martin sailer\" title=\"mioste-martin sailer\" itemprop=\"image\">\n\t\t\t\t \n\t\t<h4>Martin Sailer <\/h4>project leader\t\t\t\t\t\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/mioste.ch\/wp-content\/uploads\/bb-plugin\/cache\/mioste-matthias-buhmann-circle.jpg\" alt=\"mioste-matthias-buhmann\" title=\"mioste-matthias-buhmann\" itemprop=\"image\">\n\t\t\t\t \n\t\t<h4>Matthias Buhmann<\/h4>project leader\t\t\t\t\t\n<h2>\n\t\tMission and Vision\n\t<\/h2>\n\tOur vision is to push for\u00adward and imple\u00adment the devel\u00adop\u00adment and appli\u00adca\u00adtion of inno\u00adva\u00adtion in med\u00adi\u00adcine and surgery by con\u00adduct\u00ading research and devel\u00adop\u00adment focus\u00ading on improv\u00ading state-of-the-art tech\u00adnolo\u00adgies as well as cut\u00adting-edge tech\u00adnolo\u00adgies. We pro\u00advide sci\u00aden\u00adtif\u00adic col\u00adlab\u00ado\u00adra\u00adtion oppor\u00adtu\u00adni\u00adties based on an inter\u00adna\u00adtion\u00adal net\u00adwork with inter\u00addis\u00adci\u00adpli\u00adnary research groups. The mind\u00adset of MIOSTE is to estab\u00adlish cre\u00adative solu\u00adtions with a high lev\u00adel of reli\u00ada\u00adbil\u00adi\u00adty, effi\u00adcien\u00adcy and usabil\u00adi\u00adty.<br>\nUnit\u00ading and incor\u00adpo\u00adrat\u00ading clin\u00adi\u00adcal\u00adly ori\u00adent\u00aded and basic research activ\u00adi\u00adties with\u00adin an entre\u00adpre\u00adneur\u00adial envi\u00adron\u00adment cre\u00adates a sound hotbed for for\u00adward-look\u00ading med\u00adical inno\u00adva\u00adtions and smart tech\u00adnolo\u00adgies from bed to bench and bench to bed.\n<h2>\n\t\tSelected Publications\n\t<\/h2>\n\t<ul>\n<li>Mar\u00adgin\u00adal bone loss one year after implan\u00adta\u00adtion: a sys\u00adtem\u00adat\u00adic review of dif\u00adfer\u00adent load\u00ading pro\u00adto\u00adcols. Int J Oral Max\u00adillo\u00adfac Surg. 2020 ;49(1):121\u2013134<br>\nSom\u00admer M, Zim\u00admer\u00admann J, Grize L, St\u00fcbinger S.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>&nbsp;Diag\u00adnos\u00ading peri-implant dis\u00adease using the tongue as a 24\/7 detec\u00adtor. Nat Com\u00admun. 2017 15;8:264.<br>\nRitzer J, L\u00fch\u00admann T, Rode C, Pein-Hack\u00adel\u00adbusch M, Immohr I, Schedler U, Thiele T, St\u00fcbinger S, Rechen\u00adberg BV, Was\u00ader-Althaus J, Schlot\u00adtig F, Mer\u00adli M, Dawe H, Karp\u00ed\u0161ek M, Wyr\u00adwa R, Schn\u00adabel\u00adrauch M, Meinel L<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>&nbsp;Tita\u00adni\u00adum and hydrox\u00adya\u00adp\u00adatite coat\u00ading of poly\u00adetherether\u00adke\u00adtone and car\u00adbon fiber-rein\u00adforced poly\u00adetherether\u00adke\u00adtone: A pilot study in sheep. J Bio\u00admed Mater Res B Appl Bio\u00admater. 2016;104:1182\u201391<br>\nSt\u00fcbinger S, Drech\u00adsler A, B\u00fcr\u00adki A, Klein K, Kro\u00adnen P, von Rechen\u00adberg B<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>Osseoin\u00adte\u00adgra\u00adtion of tita\u00adni\u00adum implants func\u00adtion\u00adalised with phos\u00adpho\u00adser\u00adine-teth\u00adered poly(epsilon-lysine) den\u00addrons: a com\u00adpar\u00ada\u00adtive study with tra\u00addi\u00adtion\u00adal sur\u00adface treat\u00adments in sheep. J Mater Sci Mater Med. 2015;26:87.<br>\nSt\u00fcbinger S, Nuss K, B\u00fcr\u00adki A, Mosch I, le Sidler M, Meik\u00adle ST, von Rechen\u00adberg B, San\u00adtin M<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35822578\/\" target=\"_blank\" rel=\"noopener\">Waste\u00adwater mon\u00adi\u00adtor\u00ading of SARS-CoV\u00ad\u20112 shows high cor\u00adre\u00adla\u00adtion with COVID-19 case num\u00adbers and allowed ear\u00adly detec\u00adtion of the first con\u00adfirmed B.1.1.529 infec\u00adtion in Switzer\u00adland: results of an obser\u00adva\u00adtion\u00adal sur\u00adveil\u00adlance study.<\/a><br>\nMed Wkly. 2022 Jun 27;152:w30202. doi: 10.4414\/smw.2022.w30202. eCol\u00adlec\u00adtion 2022 Jun 20.PMID:&nbsp;35822578<br>\nBagut\u00adti C, Alt Hug M, Heim P, Mau\u00adr\u00ader Peker\u00adman L, Ilg Hampe E, H\u00fcb\u00adn\u00ader P, Fuchs S,&nbsp;Sav\u00adic M, Stadler T, Topol\u00adsky I, Icer Baykal P, Drei\u00adfuss D, Beeren\u00adwinkel N, Tschudin Sut\u00adter S.Swiss<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35243160\/\" target=\"_blank\" rel=\"noopener\">Con\u00adgen\u00adi\u00adtal orbital ter\u00adatoma: A clin\u00adi\u00adco\u00adpatho\u00adlog\u00adic case report.&nbsp;<\/a><br>\nAm J Oph\u00adthal\u00admol Case Rep. 2022 Feb 11;26:101420. doi: 10.1016\/j.ajoc.2022.101420. eCol\u00adlec\u00adtion 2022 Jun.PMID:&nbsp;35243160<br>\nRein\u00adhold A, Mey\u00ader P, Brud\u00ader E, Sole\u00adman J, von der Weid N, Mueller AA,&nbsp;Sav\u00adic M.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35410128\/\" target=\"_blank\" rel=\"noopener\">Deep\u00adSARS: simul\u00adta\u00adne\u00adous diag\u00adnos\u00adtic detec\u00adtion and genom\u00adic sur\u00adveil\u00adlance of SARS-CoV\u00ad\u20112. <\/a>BMC Genomics. 2022 Apr 11;23(1):289. doi: 10.1186\/s12864-022\u201308403\u20110.PMID:&nbsp;35410128<br>\nYer\u00admanos A, Hong KL, Agrafi\u00ado\u00adtis A, Han J, Nadeau S, Valen\u00adzuela C, Azi\u00adzoglu A, Ehling R, Gao B, Spahr M, Neumeier D, Chang CH, Dounas A, Petril\u00adlo E, Nis\u00adsen I, Bur\u00adcklen E, Feld\u00adkamp M, Beisel C, Oxe\u00adnius A,&nbsp;Sav\u00adic M, Stadler T, Rudolf F, Red\u00addy ST<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34998467\/\" target=\"_blank\" rel=\"noopener\">SARS-CoV\u00ad\u20112 reac\u00adtive and neu\u00adtral\u00adiz\u00ading anti\u00adbod\u00adies dis\u00adcov\u00adered by sin\u00adgle-cell sequenc\u00ading of plas\u00adma cells and mam\u00admalian dis\u00adplay. <\/a>Cell Rep. 2022 Jan 18;38(3):110242. doi: 10.1016\/j.celrep.2021.110242. Epub 2021 Dec 22.PMID:&nbsp;34998467<br>\nEhling RA, Weber CR, Mason DM, Frieden\u00adsohn S, Wag\u00adn\u00ader B, Bieberich F, Kapetanovic E, Vazquez-Lom\u00adbar\u00addi R, Di Rober\u00adto RB, Hong KL, Wag\u00adn\u00ader C, Pata\u00adia M, Overath MD, She\u00adward DJ, Mur\u00adrell B, Yer\u00admanos A, Cuny AP,&nbsp;Sav\u00adic M, Rudolf F, &nbsp;Red\u00addy ST<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34322127\/\" target=\"_blank\" rel=\"noopener\">A Sin\u00adgle-Cell Atlas of Lym\u00adpho\u00adcyte Adap\u00adtive Immune Reper\u00adtoires and Tran\u00adscrip\u00adtomes Reveals Age-Relat\u00aded Dif\u00adfer\u00adences in Con\u00adva\u00adles\u00adcent COVID-19 Patients.<\/a><br>\nST.Front Immunol. 2021 Jul 12;12:701085. doi: 10.3389\/fimmu.2021.701085. eCol\u00adlec\u00adtion 2021.PMID:&nbsp;34322127<br>\nBieberich F, Vazquez-Lom\u00adbar\u00addi R, Yer\u00admanos A, Ehling RA, Mason DM, Wag\u00adn\u00ader B, Kapetanovic E, Di Rober\u00adto RB, Weber CR,&nbsp;Sav\u00adic M, Rudolf F, Red\u00addy<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31519435\/\" target=\"_blank\" rel=\"noopener\">Retrob\u00adul\u00adbar haematoma in the era of anti\u00adco\u00adag\u00adu\u00adlants.<\/a><br>\nInjury. 2019 Oct;50(10):1641\u20131648. doi: 10.1016\/j.injury.2019.08.035. Epub 2019 Aug 20.PMID:&nbsp;31519435<br>\nBerg BI, Flury E, Thieringer FM, Augel\u00adlo M,&nbsp;Sav\u00adic M, Sch\u00f6tzau A, Kunz C, Gold\u00adblum D<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29543930\/\" target=\"_blank\" rel=\"noopener\">Eval\u00adu\u00ada\u00adtion of Two 3D Print\u00aders for Guid\u00aded Implant Surgery.<\/a><br>\nInt J Oral Max\u00adillo\u00adfac Implants. 2018 July\/August;33(4):743\u2013746. doi: 10.11607\/jomi.6074. Epub 2018 Mar 15.PMID:&nbsp;29543930<br>\nSom\u00admacal B,&nbsp;Sav\u00adic M*, Fil\u00adip\u00adpi A, K\u00fchl S, Thieringer FM<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24476740\/\" target=\"_blank\" rel=\"noopener\">Prog\u00aden\u00adi\u00adtor cell ther\u00ada\u00adpy for sacral pres\u00adsure sore: a pilot study with a nov\u00adel human chron\u00adic wound mod\u00adel.<\/a><br>\nStem Cell Res Ther. 2014 Jan 29;5(1):18. doi: 10.1186\/scrt407.PMID:&nbsp;24476740*Co-first author<br>\nWettstein R,&nbsp;Sav\u00adic M*, Pier\u00ader G, Scheufler O, Haug M, Hal\u00adter J, Grat\u00adwohl A, Baum\u00adberg\u00ader M, Schae\u00adfer DJ, Kalber\u00admat\u00adten DF<\/li>\n<\/ul>\n\n","protected":false},"excerpt":{"rendered":"<p>Mioste Med\u00adical Inno\u00adva\u00adtion and Smart Tech\u00adnolo\u00adgies The group \u201cMed\u00adical Inno\u00adva\u00adtion and Smart Tech\u00adnolo\u00adgies (MIOSTE)\u201d was found\u00aded by Ste\u00adfan St\u00fcbinger and Mio\u00addrag Sav\u00adic. The pri\u00adma\u00adry aim is to fos\u00adter advances in clin\u00adi\u00adcal\u00adly ori\u00adent\u00aded research, emerg\u00ading tech\u00adnolo\u00adgies and inno\u00adv\u00ada\u00adtive prod\u00aduct devel\u00adop\u00adment. Prin\u00adci\u00adpal fields of inter\u00adest are trans\u00adla\u00adtion\u00adal med\u00adi\u00adcine includ\u00ading pro\u00adto\u00adtyp\u00ading, exper\u00adi\u00admen\u00adtal sur\u00adgi\u00adcal tech\u00adniques, regen\u00ader\u00ada\u00adtive med\u00adi\u00adcine, applied biotech\u00adnol\u00ado\u00adgy\u2026<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"wp_typography_post_enhancements_disabled":false,"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mioste.ch\/index.php?rest_route=\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mioste.ch\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mioste.ch\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mioste.ch\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mioste.ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11"}],"version-history":[{"count":37,"href":"https:\/\/mioste.ch\/index.php?rest_route=\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":110,"href":"https:\/\/mioste.ch\/index.php?rest_route=\/wp\/v2\/pages\/11\/revisions\/110"}],"wp:attachment":[{"href":"https:\/\/mioste.ch\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}